What is Spravato?
A Different Approach to Depression Care
SPRAVATO® (esketamine) is a prescription nasal spray for certain adults with depression that hasn’t improved enough with antidepressants. It works differently from traditional antidepressants and is administered in our office under medical supervision, with at least two hours of monitoring after each treatment.
Your Visit
What To Expect
Get Comfortable
Settle into your treatment recliner while we check your vital signs.
Meet With Your Provider
Review your questions and discuss what to expect.
Begin Treatment
Self-administer your prescribed nasal spray under supervision.
Rest & Monitoring
Relax while our team monitors you for at least two hours.
Final Check & Heading Home
We'll check your vital signs and confirm you're ready to leave with your designated driver.
- Plan a ride home. Do not drive until the next day after a restful day of sleep.
We're here to help
Your Questions, Answered
Who may be a candidate for Spravato?
Spravato may be an option for adults with treatment-resistant depression who haven’t experienced enough improvement with antidepressants. Your provider will review your treatment history, medical history, and current symptoms to determine whether it’s appropriate for you.
How long will my appointment take?
Plan for check-in, preparation, and at least two hours of monitoring after taking Spravato. Some patients may need additional monitoring before their provider determines they’re ready to leave.
How often will I need treatment?
For treatment-resistant depression, treatment typically begins twice weekly for four weeks, followed by weekly visits for four weeks. After that, your provider may recommend treatment weekly or every other week, depending on your response.
What might I feel during treatment?
You may experience sleepiness, dizziness, nausea, or a feeling of disconnection from yourself or your surroundings. Spravato can also increase blood pressure and cause serious effects, including slowed breathing. Our team will monitor you throughout your visit. Your provider will discuss the full risks before treatment.
Can I drive myself home?
No. Arrange for a designated driver to take you home. Do not drive, operate machinery, or perform activities requiring full alertness until the next day after a restful sleep.
What should I do before my appointment?
Avoid eating for at least two hours and drinking liquids for at least 30 minutes before treatment. Review your medications with your provider and follow their instructions. Do not stop or change medications on your own.
Can I rest during my session?
Yes. You’ll relax in a comfortable recliner, and an eye mask and blanket are available. Staff will continue monitoring you and checking on your comfort while you rest.
Does insurance cover Spravato?
Coverage depends on your insurance plan and its requirements. Prior authorization may be needed. Contact our team for help understanding your benefits and potential out-of-pocket costs.
Insurance & Coverage
Questions About Coverage?
Wondering if your insurance covers Spravato® treatment? Our team can help you understand the verification process and coordinate with our billing specialists to review your benefits and potential out-of-pocket costs.
Explore your options
Spravato® or NeuroStar®TMS?
Not sure how these treatments differ? Explore our side-by-side comparison to learn about each option and discuss which may be right for you with your provider.